Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613269 | 0.85 | ALDH1A1 (0.50) | HTTKDM4EALDH1A1NPC1GAA | |
| SCHEMBL7896191 | 0.85 | ALDH1A1 (0.50) | HTTKDM4EALDH1A1NPC1GAA | |
| SCHEMBL5352485 | 0.84 | MAPT (0.41) | HTTMAPTHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL6684284 | 0.82 | ALDH1A1 (0.50) | HTTMAPTHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL10751447 | 0.79 | PAX8 (0.38) | HTTKDM4EALDH1A1NPC1GAA | |
| SCHEMBL10748285 | 0.74 | ALDH1A1 (0.41) | HTTMAPTHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL9531 | 0.72 | ATM (0.48) | ATM | |
| SCHEMBL6125492 | 0.71 | AHR (0.36) | HTTMAPTHSP90AA1KDM4ENPC1 | |
| SCHEMBL7897391 | 0.71 | CYP3A4 (0.56) | HTTMAPTHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL7900240 | 0.70 | HTT (0.42) | HTTMAPTHSP90AA1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6183934-B1 | FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0108437-B1 | PROCESS FOR THE PREPARATION OF ETHYLIDENE DIACETATE AND/OR ACETIC ACID ANHYDRIDE | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-05-14 | — | — | EP | disclosed |
| EP-0108437-A1 | Process for the preparation of ethylidene diacetate and/or acetic acid anhydride | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-05-16 | — | — | EP | disclosed |