Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 12/20 | 0.80 |
| ▸ | MEN1 | O00255 | 5/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.80 |
| ▸ | NFKBIA | P25963 | 3/20 | 0.80 |
| ▸ | RELA | Q04206 | 2/20 | 0.80 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MDM4 | O15151 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.58 |
| ▸ | G6PD | P11413 | 1/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | METAP2 | P50579 | 1/20 | 0.58 |
| ▸ | METAP1 | P53582 | 1/20 | 0.58 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460773 | 0.89 | SLC40A1 (1.00) | SLC40A1MEN1KMT2ATDP1NFKBIA | |
| SCHEMBL31676665 | 0.89 | SLC40A1 (1.00) | SLC40A1MEN1KMT2ATDP1NFKBIA | |
| SCHEMBL1507919 | 0.87 | SLC40A1 (0.76) | SLC40A1MEN1KMT2ATDP1NFKBIA | |
| SCHEMBL30854809 | 0.87 | SLC40A1 (0.76) | SLC40A1MEN1KMT2ATDP1NFKBIA | |
| SCHEMBL3780950 | 0.86 | GAA (0.76) | SLC40A1MEN1KMT2ATDP1NFKBIA | |
| SCHEMBL14919826 | 0.83 | GAA (0.71) | SLC40A1MEN1KMT2ATDP1NFKBIA | |
| SCHEMBL29540765 | 0.83 | GAA (0.71) | SLC40A1MEN1KMT2ATDP1NFKBIA | |
| SCHEMBL22234047 | 0.83 | GAA (0.71) | SLC40A1MEN1KMT2ATDP1NFKBIA | |
| SCHEMBL30925552 | 0.82 | SLC40A1 (0.78) | SLC40A1MEN1KMT2ATDP1NFKBIA | |
| SCHEMBL27214248 | 0.82 | SLC40A1 (0.78) | SLC40A1MEN1KMT2ATDP1NFKBIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180675-B1 | THERAPY FOR CHEMOKINE SENSITIVE DISEASE; USING A AROMATIC (THIO)UREA COMPOUND | SMITHKLINE BEECHAM CORPORATION | 2001-01-30 | — | — | US | disclosed |