Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.43 |
| ▸ | RXRG | P48443 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 6/20 | 0.40 |
| ▸ | RARG | P13631 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | GNRHR | P30968 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899456 | 0.81 | CYP26B1 (0.46) | RXRARXRGMAPTRXRBRARG | |
| SCHEMBL8741606 | 0.78 | RXRA (0.48) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL7879831 | 0.76 | RARG (0.52) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL7879827 | 0.76 | RARG (0.52) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL8336498 | 0.73 | RXRA (0.47) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL7897279 | 0.72 | RXRA (0.45) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL16852879 | 0.72 | MAPT (0.56) | MAPTALDH1A1TTRDPP4 | |
| SCHEMBL22001266 | 0.71 | RXRA (0.54) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL14785551 | 0.71 | RXRA (0.43) | RXRARXRGRXRBRARGRARB | |
| SCHEMBL14785552 | 0.71 | RXRA (0.43) | RXRARXRGRXRBRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258775-B1 | 3-(3-(5,5,8,8-TETRAMATHYL-5,6,7,8-TETRAHYDRO-2-NAPHTYLCARBONYL )PHENYL)ACRYLIC ACID FOR TREATING DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 2001-07-10 | — | — | US | disclosed |