Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 5/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.36 |
| ▸ | CCR2 | P41597 | 5/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899532 | 0.84 | GRIA2 (0.44) | GRIA2 | |
| SCHEMBL7898940 | 0.83 | GRIA2 (0.58) | GRIA2TRPV1CCR2CYP11B1CYP11B2 | |
| SCHEMBL7898318 | 0.80 | GRIA2 (0.47) | GRIA2TRPV1CCR2CYP11B1CYP11B2 | |
| SCHEMBL11898515 | 0.78 | GRIA2 (0.70) | GRIA2TRPV1CCR2BDKRB1 | |
| SCHEMBL7903113 | 0.75 | GRIA2 (0.43) | GRIA2TRPV1CCR2BDKRB1 | |
| SCHEMBL7897262 | 0.75 | GRIA2 (0.43) | GRIA2TRPV1CCR2 | |
| SCHEMBL15327849 | 0.74 | TRPV1 (0.46) | GRIA2TRPV1CCR2BDKRB1 | |
| SCHEMBL15338340 | 0.74 | CCR2 (0.40) | GRIA2TRPV1CCR2 | |
| SCHEMBL7899877 | 0.74 | HTR1A (0.44) | GRIA2TRPV1CCR2BDKRB1 | |
| SCHEMBL7897265 | 0.71 | GRIA2 (0.36) | GRIA2TRPV1CCR2BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010115952-A1 | INDANE DERIVATIVES | N.V. ORGANON (NL) | 2010-10-14 | — | — | WO | disclosed |