Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7892372 | 1.00 | FDPS (0.43) | FDPSFGFR1FGFR4HDAC6P2RX7 | |
| SCHEMBL7898274 | 0.86 | HSP90AB1 (0.46) | — | |
| SCHEMBL7623763 | 0.86 | HSP90AB1 (0.46) | — | |
| SCHEMBL7892344 | 0.86 | HSP90AB1 (0.46) | — | |
| SCHEMBL7892156 | 0.86 | HSP90AB1 (0.46) | — | |
| SCHEMBL7892176 | 0.86 | HSP90AB1 (0.46) | — | |
| SCHEMBL7620624 | 0.76 | PNP (0.50) | — | |
| SCHEMBL7619346 | 0.76 | HSP90AA1 (0.32) | — | |
| SCHEMBL7892366 | 0.74 | KDM4E (0.39) | HDAC6 | |
| SCHEMBL3981358 | 0.71 | FDPS (0.67) | FDPSFGFR1FGFR4HDAC6P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789394-A | VIRICIDES FOR CYTOMEGALOVIRUS USING NUCLEOTIDES | NGUYEN-BA NGHE (CA) | 1998-08-04 | — | — | US | claimed |
| US-6194576-B1 | COUPLING PURINE OR PYRIMIDINE BASE WITH NUCLEOTIDE ANALOG PHOSPHONATE COMPOUND | BIOCHEM PHARMA, INC. (CA) | 2001-02-27 | — | — | US | disclosed |
| US-6127540-A | NUCLEOTIDE ANALOGS MADE BY COUPLING A PURINE OR PYRIMIDINE NUCLEOTIDE BASE OR ANALOGUE THEREOF WITH A 2-(PHOSPHONATE)FURAN OR 2-(PHOSPHONATE)THIOFURAN OF GIVEN FORMULA; USE AS NON-TOXIC ANTIVIRAL DRUGS | BIOCHEM PHARMA, INC. (CA) | 2000-10-03 | — | — | US | disclosed |
| US-6005107-A | Antiviral compounds | BIOCHEM PHARMA, INC. (CA) | 1999-12-21 | — | — | US | disclosed |
| US-5955610-A | COUPLING PHOSPHONATE INTERMEDIATE WITH PURINE OR PYRIMIDINE NUCLEOTIDE BASE | BIOCHEM PHARMA, INC. (CA) | 1999-09-21 | — | — | US | disclosed |
| US-5789394-A | VIRICIDES FOR CYTOMEGALOVIRUS USING NUCLEOTIDES | NGUYEN-BA NGHE (CA) | 1998-08-04 | — | — | US | disclosed |