Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | FPR3 | P25089 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900007 | 0.78 | USP30 (0.44) | CHRM1USP30ACKR3BRD4BCHE | |
| SCHEMBL19816138 | 0.71 | NR1H2 (0.44) | CHRM1FPR3FPR2ACKR3MEN1 | |
| SCHEMBL31561483 | 0.67 | GPR119 (0.43) | — | |
| SCHEMBL17207589 | 0.65 | ACKR3 (0.57) | CYP2C9ACKR3MEN1ALDH1A1MAPT | |
| SCHEMBL3002618 | 0.65 | ACKR3 (0.57) | CYP2C9ACKR3MEN1ALDH1A1MAPT | |
| SCHEMBL3002627 | 0.65 | ACKR3 (0.57) | CYP2C9ACKR3MEN1ALDH1A1MAPT | |
| SCHEMBL25047542 | 0.65 | MEN1 (0.55) | USP30MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL12808125 | 0.65 | MEN1 (0.55) | USP30MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL31683762 | 0.65 | MEN1 (0.55) | USP30MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL17518859 | 0.64 | MEN1 (0.51) | FPR3FPR2USP30MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |