SCHEMBL7898477

SCHEMBL7898477

Nc1ccc2cc(O)cc(S(=O)(=O)O)c2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 3/20 0.58
CASP6 P55212 4/20 0.46
NSD2 O96028 2/20 0.46
DUSP3 P51452 1/20 0.46
PTPN5 P54829 1/20 0.46
PTPN11 Q06124 1/20 0.46
RAPGEF4 Q8WZA2 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
ALDH1A1 P00352 7/20 0.41
HSD17B10 Q99714 4/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
TDP1 Q9NUW8 4/20 0.41
RECQL P46063 3/20 0.41
KDM4E B2RXH2 2/20 0.41
POLB P06746 2/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
APEX1 P27695 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10528060 0.88 CASP6 (0.57) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL11227398 0.86 CASP6 (0.55) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL6559611 0.85 NT5E (0.57) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL4650562 0.83 MPL (0.50) NT5ECASP6NSD2HSD17B10TDP1
SCHEMBL8968523 0.82 NT5E (0.73) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL8713026 0.82 NT5E (0.73) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL151762 0.82 NT5E (0.73) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL29392802 0.82 NT5E (0.73) NT5ECASP6NSD2DUSP3PTPN5
Water SCHEMBL28374688 0.81 NT5E (0.71) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL8008839 0.81 NT5E (0.71) NT5ECASP6NSD2DUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0231147-B1 PROCESS FOR THE TRICHROMATIC DYEING OF LEATHER CIBA-GEIGY AG (CH) 1992-01-15 EP claimed
US-4799933-A COLORFAST MIXTURE OF A YELLOW AND RED DYE AND A GRAY; CHROMIUM-METALLIZED AZO OR AZO-METHINE DYES CIBA-GEIGY CORPORATION (US) 1989-01-24 US claimed
EP-0231147-A2 Process for the trichromatic dyeing of leather CIBA-GEIGY AG (CH) 1987-08-05 EP claimed
US-6194554-B1 DYEING AND PRINTING MATERIALS CONTAINING CARBOXAMIDE GROUPS AND/OR CELLULOSIC MATERIALS BY APPLYING DISAZO DYE BAYER AKTIENGESELLSCHAFT (DE) 2001-02-27 US disclosed
EP-0919596-A1 Disazo dyes Bayer Aktiengesellschaft (DE) 1999-06-02 EP disclosed
EP-0542082-B1 Process for continuously reacting difluortriazinyl compounds with amines BAYER AG (DE) 1998-02-25 EP disclosed
EP-0542079-B1 Process for continuously reacting halogenopyrimidines with amines BAYER AG (DE) 1997-07-23 EP disclosed
US-5440039-A Process for the continuous reaction of cyanuric fluoride with amines and a reactor for carrying out this process BAYER AKTIENGESELLSCHAFT (DE) 1995-08-08 US disclosed
US-5420255-A Process for the continuous reaction of halogenopyrimidines with amines BAYER AKTIENGESELLSCHAFT (DE) 1995-05-30 US disclosed
EP-0458110-B1 Process for continuous reaction of cyanuric fluoride with amines. BAYER AG (DE) 1994-12-14 EP disclosed
US-5332813-A Process for the continuous reaction of difluorotriazinyl compounds with amines BAYER AKTIENGESELLSCHAFT (DE) 1994-07-26 US disclosed
EP-0016931-A2 Reactive azo dyestuffs, their use in dyeing and printing materials containing amide or hydroxyl groups BAYER AG (DE) 1980-10-15 EP disclosed
US-4216166-A Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction AMERICAN CYANAMID COMPANY (US) 1980-08-05 US disclosed
US-4189570-A Difluoro-s-triazinylamino-hydroxynaphthalene-sulfonic acid CIBA-GEIGY CORPORATION (US) 1980-02-19 US disclosed
EP-0003767-A1 N-Acylaminohydroxynaphthalenesulfonic acid salts, process for their preparation and their use as coupling components in the preparation of azo dyes. BAYER AG (DE) 1979-09-05 EP disclosed
US-4105400-A SHADES OF BLACK, BROWN AND NAVY BLUE; TOGETHER WITH LEVELLING AGENT CIBA-GEIGY CORPORATION (US) 1978-08-08 US disclosed
US-RE29585-E DYEING WOOL CIBA-GEIGY CORPORATION (US) 1978-03-21 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3966703-A Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed
US-3933785-A Azo compounds CIBA-GEIGY AG (CH) 1976-01-20 US disclosed