Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 1.00 |
| ▸ | MMP13 | P45452 | 12/20 | 1.00 |
| ▸ | MMP3 | P08254 | 10/20 | 1.00 |
| ▸ | MMP1 | P03956 | 3/20 | 0.76 |
| ▸ | MMP9 | P14780 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7450983 | 0.90 | MMP2 (1.00) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7452549 | 0.90 | MMP2 (0.82) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7503190 | 0.87 | MMP2 (1.00) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7455660 | 0.84 | MMP13 (0.73) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7451546 | 0.82 | MMP2 (0.85) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7454871 | 0.81 | MMP2 (1.00) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7455836 | 0.81 | MMP2 (1.00) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL7892635 | 0.78 | MMP2 (1.00) | MMP2MMP13MMP3MMP1LMNA | |
| SCHEMBL7451531 | 0.77 | MMP13 (0.80) | MMP2MMP13MMP3MMP1MMP9 | |
| SCHEMBL4327772 | 0.76 | MMP13 (1.00) | MMP2MMP13MMP3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |