Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | KAT7 | O95251 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905938 | 0.79 | ALOX5AP (0.37) | ALOX5APFEN1CYP2C9GPR119HPGDS | |
| SCHEMBL7893412 | 0.78 | ALOX5AP (0.39) | ALOX5APFEN1GPR119SCN9A | |
| SCHEMBL2789050 | 0.76 | PIK3CD (0.39) | ALOX5APFEN1PIK3CDCYP2C9NSD2 | |
| SCHEMBL2789048 | 0.76 | PIK3CD (0.39) | ALOX5APFEN1PIK3CDCYP2C9NSD2 | |
| SCHEMBL7902460 | 0.76 | MEN1 (0.40) | ALOX5APFEN1GPR119SCN9AKAT7 | |
| SCHEMBL7897488 | 0.75 | USP30 (0.42) | SCN9AMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7898507 | 0.74 | KAT7 (0.39) | ALOX5APFEN1CYP2C9GPR119SCN9A | |
| SCHEMBL7899660 | 0.74 | USP30 (0.41) | ALOX5APFEN1GPR119SCN9AKAT7 | |
| SCHEMBL7898814 | 0.72 | HTR6 (0.39) | ALOX5APFEN1GPR119SCN9AKAT7 | |
| SCHEMBL7896607 | 0.72 | HTR6 (0.41) | MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |