Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AHCY | P23526 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896607 | 0.83 | HTR6 (0.41) | USP30ANO1MEN1KMT2AALDH1A1 | |
| SCHEMBL7899660 | 0.80 | USP30 (0.41) | USP30CNR1CNR2ANO1MEN1 | |
| SCHEMBL7893412 | 0.79 | ALOX5AP (0.39) | USP30KDM1ASCN9A | |
| SCHEMBL7898814 | 0.79 | HTR6 (0.39) | USP30MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7902460 | 0.79 | MEN1 (0.40) | USP30MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7898507 | 0.79 | KAT7 (0.39) | ANO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7905938 | 0.78 | ALOX5AP (0.37) | USP30ANO1MEN1KMT2AALDH1A1 | |
| SCHEMBL7896805 | 0.77 | HTR6 (0.46) | USP30MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7898501 | 0.75 | ALOX5AP (0.36) | MEN1KMT2AALDH1A1MAPTSCN9A | |
| SCHEMBL7900007 | 0.74 | USP30 (0.44) | USP30KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |