Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11658096 | 0.81 | DNM1 (0.37) | — | |
| SCHEMBL49737 | 0.81 | ERBB2 (0.62) | ERBB2HKDC1KDM4ECYP3A4MAPT | |
| SCHEMBL28259188 | 0.78 | ERBB2 (0.59) | ERBB2HKDC1KDM4ECYP3A4MAPT | |
| SCHEMBL28856262 | 0.78 | ERBB2 (0.59) | ERBB2HKDC1KDM4ECYP3A4MAPT | |
| SCHEMBL7898541 | 0.76 | HSP90AA1 (0.45) | ERBB2HKDC1KDM4ECYP3A4MAPT | |
| SCHEMBL11412094 | 0.75 | HSP90AA1 (0.44) | ERBB2HKDC1KDM4ECYP3A4MAPT | |
| SCHEMBL11419341 | 0.71 | DNM1 (0.71) | HKDC1KDM4ECYP3A4MAPTALOX15 | |
| SCHEMBL10079171 | 0.70 | ALOX5 (0.49) | ALOX5 | |
| SCHEMBL3417111 | 0.70 | HKDC1 (0.56) | ERBB2HKDC1KDM4ECYP3A4MAPT | |
| Coprinin SCHEMBL3416504 | 0.70 | ERBB2 (0.50) | ERBB2HKDC1KDM4ECYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4107147-A1 | NOVEL PHENAZINE-BASED COMPOUNDS | CMBlu Energy AG (DE) | 2022-12-28 | — | — | EP | disclosed |