Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 13/20 | 0.65 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.65 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.61 |
| ▸ | PI4KA | P42356 | 7/20 | 0.61 |
| ▸ | MTOR | P42345 | 4/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790675 | 0.88 | PIK3CA (0.69) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL789911 | 0.85 | PIK3CG (0.77) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL789336 | 0.83 | PIK3CA (0.61) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL807071 | 0.82 | PIK3CA (0.60) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL806732 | 0.80 | PI4KA (0.68) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL14247779 | 0.79 | PIK3CA (0.74) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL790131 | 0.79 | PIK3CD (0.56) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL791380 | 0.77 | PIK3CG (0.66) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL10277562 | 0.77 | PIK3CG (0.76) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL789466 | 0.77 | PIK3CA (0.67) | PIK3CAPIK3R1PIK3CGPI4KAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |