Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 16/20 | 0.60 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.60 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.54 |
| ▸ | PI4KA | P42356 | 4/20 | 0.54 |
| ▸ | MTOR | P42345 | 5/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789336 | 0.94 | PIK3CA (0.61) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL807367 | 0.87 | PIK3CG (0.69) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL790675 | 0.85 | PIK3CA (0.69) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL789863 | 0.82 | PIK3CA (0.65) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL790863 | 0.81 | PIK3CG (0.69) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL806978 | 0.78 | PIK3CG (0.83) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL790131 | 0.77 | PIK3CD (0.56) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL789466 | 0.75 | PIK3CA (0.67) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL807260 | 0.75 | PIK3CA (0.58) | PIK3CAPIK3R1PIK3CGPI4KAMTOR | |
| SCHEMBL807022 | 0.74 | PIK3CG (0.85) | PIK3CAPIK3R1PIK3CGPI4KAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |