Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.51 |
| ▸ | PI4KA | P42356 | 6/20 | 0.50 |
| ▸ | MTOR | P42345 | 4/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790675 | 0.86 | PIK3CA (0.69) | PIK3CDPIK3CGPIK3CAPIK3R1PI4KA | |
| SCHEMBL790102 | 0.81 | PIK3CG (0.66) | PIK3CDPIK3CGPIK3CAPIK3R1PI4KA | |
| SCHEMBL789863 | 0.79 | PIK3CA (0.65) | PIK3CDPIK3CGPIK3CAPIK3R1PI4KA | |
| SCHEMBL807071 | 0.77 | PIK3CA (0.60) | PIK3CDPIK3CGPIK3CAPIK3R1PI4KA | |
| SCHEMBL789336 | 0.76 | PIK3CA (0.61) | PIK3CDPIK3CGPIK3CAPIK3R1PI4KA | |
| SCHEMBL807260 | 0.75 | PIK3CA (0.58) | PIK3CDPIK3CGPIK3CAPIK3R1PI4KA | |
| SCHEMBL807092 | 0.74 | PI4KA (0.55) | PIK3CDPIK3CGPIK3CAPI4KAMTOR | |
| SCHEMBL789466 | 0.74 | PIK3CA (0.67) | PIK3CDPIK3CGPIK3CAPIK3R1PI4KA | |
| SCHEMBL790763 | 0.74 | PIK3CG (0.62) | PIK3CDPIK3CGPIK3CAPI4KAMTOR | |
| SCHEMBL790421 | 0.73 | APP (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |