Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893126 | 0.72 | S1PR3 (0.41) | S1PR3PPARAPPARGPLA2G6PLA2G4A | |
| SCHEMBL7892968 | 0.71 | ABCB1 (0.40) | — | |
| SCHEMBL18109330 | 0.69 | ABCB1 (0.43) | MEN1POLBKMT2ACNR2 | |
| SCHEMBL8518305 | 0.64 | LPL (0.66) | PPARAPPARGLPLLIPG | |
| Setogepram SCHEMBL289216 | 0.64 | ALDH1A1 (0.69) | PPARAPPARGLPLLIPG | |
| Setogepram SCHEMBL29395927 | 0.64 | ALDH1A1 (0.69) | PPARAPPARGLPLLIPG | |
| SCHEMBL288982 | 0.64 | PPARA (0.60) | PPARAPPARGLPLLIPG | |
| Propionic Acid SCHEMBL29170106 | 0.63 | PPARA (0.59) | PPARAPPARGLPLLIPG | |
| SCHEMBL7257290 | 0.63 | LPL (0.61) | PPARAPPARGLPLLIPG | |
| SCHEMBL25173309 | 0.63 | MAPT (0.66) | S1PR3PPARAPPARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319702-B1 | NUCLEOTIDE SEQUENCS CODING AN ENZYMATIC POLYPEPTIDE AND CELL TARGETING COMPOUND; FOR USE IN TREATMENT OF CANCER | GLAXO WELLCOME, INC. | 2001-11-20 | — | — | US | disclosed |