Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 5/20 | 0.53 |
| ▸ | TOP1 | P11387 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | IDO1 | P14902 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | AURKA | O14965 | 2/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | P4HB | P07237 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951213 | 0.74 | KMT2A (0.65) | MEN1KMT2AALDH1A1THRBBLM | |
| SCHEMBL7899015 | 0.72 | PTPRC (0.46) | CDC25BTOP1MEN1KMT2AIDO1 | |
| SCHEMBL3612898 | 0.71 | LMNA (0.55) | MEN1KMT2AALDH1A1THRBBLM | |
| SCHEMBL30086144 | 0.71 | LMNA (0.55) | MEN1KMT2AALDH1A1THRBBLM | |
| SCHEMBL5158317 | 0.71 | MAPT (0.48) | CDC25BMEN1KMT2AALDH1A1THRB | |
| SCHEMBL30173417 | 0.71 | ADORA2A (0.53) | CDC25BMEN1KMT2AALDH1A1THRB | |
| SCHEMBL3247246 | 0.71 | ADORA2A (0.53) | CDC25BMEN1KMT2AALDH1A1THRB | |
| SCHEMBL2079477 | 0.71 | KMT2A (0.50) | CDC25BMEN1KMT2AALDH1A1THRB | |
| SCHEMBL10432889 | 0.71 | TDP1 (0.46) | MEN1KMT2AALDH1A1THRBBLM | |
| SCHEMBL327050 | 0.70 | ALDH1A1 (0.57) | CDC25BTOP1MEN1KMT2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265220-B1 | NON-IMMUNOCHEMICAL METHOD BY REACTING A COMPOUND COMPRISING CIS-1,4-DIOXO-2-BUTENE MOIETY OR HYDROLYTICALLY DERIVED PRECURSOR WITH HOMOCYSTEINE, THEN DETECTING PRODUCT WITHOUT SEPARATION FROM LIQUID | ULLMAN EDWIN F (US) | 2001-07-24 | — | — | US | disclosed |
| WO-2000000821-A1 | ASSAY FOR HOMOCYSTEINE | ULLMAN EDWIN F (US) | 2000-01-06 | — | — | WO | disclosed |