Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7877078 | 0.98 | MAOB (0.59) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL7876990 | 0.95 | MAOB (0.54) | MAOBGAAMAPTMAOARAB9A | |
| Hydrochloric Acid SCHEMBL7406333 | 0.88 | MAOB (0.59) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL17024339 | 0.86 | LMNA (0.58) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL419050 | 0.85 | APP (0.69) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL10013799 | 0.85 | LMNA (0.60) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL16016779 | 0.85 | LMNA (0.60) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL8866033 | 0.85 | MAOB (0.59) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL13279971 | 0.84 | MAOB (0.73) | MAOBMAOAAPP | |
| SCHEMBL1681364 | 0.84 | SMN1; SMN2 (0.60) | MAOBGAAMAPTMAOARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200993-B1 | ASTHMA; ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA & CO. (CA) | 2001-03-13 | — | — | US | disclosed |