Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.69 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.66 |
| ▸ | RXRA | P19793 | 1/20 | 0.66 |
| ▸ | RXRB | P28702 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12732314 | 0.95 | APP (0.63) | APPNR4A2RXRARXRBCYP2C19 | |
| SCHEMBL12264541 | 0.92 | APP (0.69) | APPNR4A2RXRARXRBCYP2C19 | |
| SCHEMBL22275947 | 0.90 | APP (0.82) | APPNR4A2RXRARXRBLMNA | |
| SCHEMBL13439802 | 0.90 | APP (0.66) | APPNR4A2RXRARXRBCYP2C19 | |
| SCHEMBL10013799 | 0.89 | LMNA (0.60) | APPNR4A2RXRARXRBCYP2C19 | |
| SCHEMBL16016779 | 0.89 | LMNA (0.60) | APPNR4A2RXRARXRBCYP2C19 | |
| SCHEMBL1681364 | 0.87 | SMN1; SMN2 (0.60) | APPNR4A2CYP2C19LMNACYP1A2 | |
| SCHEMBL15372302 | 0.85 | LMNA (0.56) | APPNR4A2CYP2C19LMNACYP1A2 | |
| SCHEMBL7899077 | 0.85 | MAOB (0.59) | APPNR4A2CYP2C19LMNACYP1A2 | |
| SCHEMBL4602365 | 0.85 | LMNA (0.61) | APPNR4A2RXRARXRBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58224786-A | — | — | None | — | — | JP | disclosed |
| JP-59155096-A | — | — | None | — | — | JP | disclosed |
| US-20240228463-A1 | SODIUM CHANNEL INHIBITORS AND METHODS OF DESIGNING SAME | GENENTECH, INC. (US) | 2024-07-11 | — | — | US | disclosed |
| US-20240228463-A1 | SODIUM CHANNEL INHIBITORS AND METHODS OF DESIGNING SAME | GENENTECH, INC. (US) | 2024-07-11 | — | — | US | disclosed |
| US-11814452-B2 | Aziridine polymers whose chemical structural changes are induced by mechanical force | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2023-11-14 | — | — | US | disclosed |
| US-11814452-B2 | Aziridine polymers whose chemical structural changes are induced by mechanical force | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2023-11-14 | — | — | US | disclosed |
| US-20210393623-A1 | Novel Heterocyclic Derivatives Useful as SHP2 Inhibitors | JACOBIO PHARMACEUTICALS CO LTD (CN) | 2021-12-23 | — | — | US | disclosed |
| US-20210371557-A1 | AZIRIDINE POLYMERS WHOSE CHEMICAL STRUCTURAL CHANGES ARE INDUCED BY MECHANICAL FORCE | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2021-12-02 | — | — | US | disclosed |
| US-20200055823-A1 | QUINOLONE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2020-02-20 | — | — | US | disclosed |
| US-10301306-B2 | Substituted dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-ones as RIPK3 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-05-28 | — | — | US | disclosed |
| US-20070135600-A1 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | US | disclosed |
| US-20070135600-A1 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | US | disclosed |
| US-20070123576-A1 | Compounds inducing differentiation of myoblasts or muscle fibers into neuron cells, pharmaceutical composition including said compounds, a method for inducing neuron differentiation and a screening method for identifying additional compounds useful for inducing neuron differentiation | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2007-05-31 | — | — | US | disclosed |
| US-7217712-B2 | 4-Substituted-5-cyano-1H-pyrimidin-6-(thi)ones as GSK-3 inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2007-05-15 | — | — | US | disclosed |
| US-20070037855-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | ALZHEIMER'S INSTITUTE OF AMERICA, INC. | 2007-02-15 | — | — | US | disclosed |
| US-4682193-A | HEAT SENSITIVE, STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1987-07-21 | — | — | US | disclosed |
| US-4480052-A | COLORLESS DYE, PHENOL DERIVATIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| US-4471073-A | FATTY AMIDES, BISPHENOL COMPOUNDS, DYES | FUJI PHOTO FILM CO., LTD. (JP) | 1984-09-11 | — | — | US | disclosed |
| JP-S59155096-A | THERMAL RECORDING PAPER | OJI PAPER CO LTD | 1984-09-04 | — | — | JP | disclosed |
| JP-S58224786-A | TRANSFER TYPE HEAT-SENSITIVE RECORDING MATERIAL | FUJI PHOTO FILM CO LTD | 1983-12-27 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055823-A1 | QUINOLONE COMPOUND | HAX1, NQO2, NHERF1 | APP 4377/4885NR4A2 2817/4885RXRA 1532/4885 |
| US-20070135600-A1 | Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex | AP1M1, OR10J3, AP2M1 | APP 2224/4885NR4A2 1101/4885RXRA 1451/4885 |
| US-10301306-B2 | Substituted dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-ones as RIPK3 inhibitors | RIPK3, RIPK1, RIPK4 | APP 3554/4885NR4A2 2159/4885RXRA 1188/4885 |
| US-20070037855-A1 | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds | APP, PSEN1, PSEN2 | APP 1/4885NR4A2 1559/4885RXRA 3888/4885 |
| US-20240228463-A1 | SODIUM CHANNEL INHIBITORS AND METHODS OF DESIGNING SAME | CACNA1I, CACNA1B, CACNA1C | APP 2607/4885NR4A2 3351/4885RXRA 4348/4885 |
| US-20070123576-A1 | Compounds inducing differentiation of myoblasts or muscle fibers into neuron cells, pharmaceutical composition including said compounds, a method for inducing neuron differentiation and a screening method for identifying additional compounds useful for inducing neuron differentiation | TNNC1, TNNI3, PYGM | APP 984/4885NR4A2 533/4885RXRA 282/4885 |
| US-20210393623-A1 | Novel Heterocyclic Derivatives Useful as SHP2 Inhibitors | PTPN1, PTPN5, PTPN2 | APP 3711/4885NR4A2 980/4885RXRA 2306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.