Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425471 | 0.85 | TRPV1 (0.44) | TRPV1ALDH1A1SMN1; SMN2USP2TRPA1 | |
| SCHEMBL427875 | 0.83 | HCAR3 (0.46) | TRPV1ALDH1A1SMN1; SMN2USP2HCAR3 | |
| SCHEMBL427978 | 0.83 | KCNMA1 (0.50) | TRPV1ALDH1A1SMN1; SMN2USP2TRPA1 | |
| SCHEMBL424342 | 0.82 | TRPV1 (0.53) | TRPV1ALDH1A1USP2TRPA1MGLL | |
| SCHEMBL427404 | 0.81 | HCAR3 (0.44) | TRPV1ALDH1A1SMN1; SMN2USP2HCAR3 | |
| SCHEMBL427316 | 0.81 | TRPV1 (0.48) | TRPV1ALDH1A1SMN1; SMN2USP2TRPA1 | |
| SCHEMBL427980 | 0.81 | MGAM (0.47) | TRPV1ALDH1A1SMN1; SMN2USP2TRPA1 | |
| SCHEMBL424622 | 0.80 | KMT2A (0.51) | TRPV1ALDH1A1TRPA1MGLLHPGD | |
| SCHEMBL425717 | 0.79 | TRPV1 (0.45) | TRPV1ALDH1A1SMN1; SMN2USP2TRPA1 | |
| SCHEMBL426739 | 0.78 | TRPV1 (0.50) | TRPV1ALDH1A1SMN1; SMN2USP2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074588-A2 | PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & Cª, S.A. (PT) | 2010-07-01 | — | — | WO | disclosed |