Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL63913 | 1.00 | KDM4E (0.51) | KDM4EPKMADORA3ADORA1ADORA2A | |
| SCHEMBL934381 | 1.00 | KDM4E (0.51) | KDM4EPKMADORA3ADORA1ADORA2A | |
| SCHEMBL7751930 | 1.00 | KDM4E (0.51) | KDM4EPKMADORA3ADORA1ADORA2A | |
| SCHEMBL63914 | 1.00 | KDM4E (0.51) | KDM4EPKMADORA3ADORA1ADORA2A | |
| SCHEMBL1274810 | 0.86 | ADORA3 (0.51) | KDM4EPKMADORA3ADORA1 | |
| SCHEMBL1274809 | 0.86 | ADORA3 (0.51) | KDM4EPKMADORA3ADORA1 | |
| SCHEMBL1707366 | 0.86 | ADORA3 (0.51) | KDM4EPKMADORA3ADORA1 | |
| SCHEMBL29389281 | 0.86 | ADORA3 (0.51) | KDM4EPKMADORA3ADORA1 | |
| SCHEMBL28894185 | 0.86 | ADORA3 (0.54) | KDM4EPKMADORA3ADORA1 | |
| SCHEMBL28894183 | 0.86 | ADORA3 (0.54) | KDM4EPKMADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3472344-A1 | COMPOSITIONS AND METHODS FOR DETECTING PREDISPOSITION TO CARDIOVASCULAR DISEASE | University Of Iowa Research Foundation (US) | 2019-04-24 | — | — | EP | disclosed |
| WO-2017214397-A1 | COMPOSITIONS AND METHODS FOR DETECTING PREDISPOSITION TO CARDIOVASCULAR DISEASE | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2017-12-14 | — | — | WO | disclosed |
| WO-2014186361-A2 | PHARMACOGENOMIC BIOMARKERS FOR B CELL MALIGNANCIES AND METHODS OF USE THEREOF | CHEN WEI (US) | 2014-11-20 | — | — | WO | disclosed |
| EP-1161560-A1 | ELECTROPOLYMERIZABLE FILM, AND METHOD OF MAKING AND USE THEREOF | The University of North Carolina at Chapel Hill (US) | 2001-12-12 | — | — | EP | disclosed |
| US-6180346-B1 | ELECTROCHEMICAL DETECTION OF NUCLEIC ACIDS | THE UNIVERSTIY OF NORTH CAROLINA AT CHAPEL HILL | 2001-01-30 | — | — | US | disclosed |
| WO-2000055366-A1 | ELECTROPOLYMERIZABLE FILM, AND METHOD OF MAKING AND USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-09-21 | — | — | WO | disclosed |
| US-5968745-A | ELECTRODE OF SUBSTRATE HAVING ELECTROCONDUCTIVE WORKING SURFACE AND A NONCONDUCTIVE OUTER POLYMER LAYER WHERE PROBES CAN BE ATTACHED HAVING MICROFLUIDIC REACTION OPENINGS FOR TRANSITION METAL COMPLEX TO TRANSFER ELECTRONS TO SURFACE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1999-10-19 | — | — | US | disclosed |