Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899387 | 1.00 | CA1 (0.48) | CA1CA2MAPTLMNASMN1; SMN2 | |
| SCHEMBL7908674 | 0.92 | EPHX2 (0.54) | CA1CA2MAPTLMNASMN1; SMN2 | |
| SCHEMBL7908678 | 0.92 | EPHX2 (0.54) | CA1CA2MAPTLMNASMN1; SMN2 | |
| SCHEMBL5494077 | 0.86 | SMN1; SMN2 (0.43) | CA1CA2MAPTLMNASMN1; SMN2 | |
| SCHEMBL5186521 | 0.86 | SMN1; SMN2 (0.43) | CA1CA2MAPTLMNASMN1; SMN2 | |
| SCHEMBL5186509 | 0.86 | SMN1; SMN2 (0.43) | CA1CA2MAPTLMNASMN1; SMN2 | |
| SCHEMBL7905596 | 0.84 | SMN1; SMN2 (0.45) | MAPTLMNASMN1; SMN2NR1H4EPHX2 | |
| SCHEMBL7905599 | 0.84 | SMN1; SMN2 (0.45) | MAPTLMNASMN1; SMN2NR1H4EPHX2 | |
| SCHEMBL6567600 | 0.80 | ALDH1A1 (0.47) | MAPTLMNASMN1; SMN2NR1H4EPHX2 | |
| SCHEMBL6567605 | 0.80 | ALDH1A1 (0.47) | MAPTLMNASMN1; SMN2NR1H4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207857-B1 | FOR ORGANOLEPTIC AND ANTIMICROBIAL COMPOUNDS GENERATED IN THE PRESENCE OF SKIN BACTERIA, ENZYMES OR ACIDIC OR ALKALINE CONDITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2001-03-27 | — | — | US | claimed |
| US-6207857-B1 | FOR ORGANOLEPTIC AND ANTIMICROBIAL COMPOUNDS GENERATED IN THE PRESENCE OF SKIN BACTERIA, ENZYMES OR ACIDIC OR ALKALINE CONDITIONS | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 2001-03-27 | — | — | US | disclosed |
| EP-0887336-A1 | Precursor Compounds | GIVAUDAN-ROURE (INTERNATIONAL) SA (CH) | 1998-12-30 | — | — | EP | disclosed |