Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | ESRRB | O95718 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186509 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAMAPTNR1H4EPHX2 | |
| SCHEMBL5186521 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAMAPTNR1H4EPHX2 | |
| SCHEMBL7905599 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAMAPTNR1H4EPHX2 | |
| SCHEMBL7905596 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAMAPTNR1H4EPHX2 | |
| SCHEMBL7899387 | 0.86 | CA1 (0.48) | SMN1; SMN2LMNAMAPTNR1H4EPHX2 | |
| SCHEMBL11462769 | 0.86 | NPC1 (0.37) | SMN1; SMN2LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL7899385 | 0.86 | CA1 (0.48) | SMN1; SMN2LMNAMAPTNR1H4EPHX2 | |
| SCHEMBL6567605 | 0.84 | ALDH1A1 (0.47) | SMN1; SMN2LMNAMAPTNR1H4EPHX2 | |
| SCHEMBL6567600 | 0.84 | ALDH1A1 (0.47) | SMN1; SMN2LMNAMAPTNR1H4EPHX2 | |
| SCHEMBL6568186 | 0.83 | LMNA (0.50) | SMN1; SMN2LMNAMAPTNR1H4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1609775-B1 | 1-acetoxy-3-(substituted phenyl) propen compounds useful as an intermediate material | UBE INDUSTRIES (JP) | 2007-06-27 | — | — | EP | disclosed |
| EP-1574509-B1 | PROCESS FOR THE PRODUCTION OF 1-ACETOXY-3-(SUBSTITUTED PHENYL)PROPENES | UBE INDUSTRIES (JP) | 2007-06-13 | — | — | EP | disclosed |
| US-7173148-B2 | Process for producing 1-acetoxy-3-(substituted phenyl)propene compound | UBE INDUSTRIES, LTD. (JP) | 2007-02-06 | — | — | US | disclosed |
| US-20060069273-A1 | Process for producing 1-acetoxy-3-(substituded phenyl) propenes | UBE INDUSTRIES, LTD. (JP) | 2006-03-30 | — | — | US | disclosed |
| US-20060004213-A1 | 1-Acetoxy-3-(substituted phenyl)propene compounds | UBE INDUSTRIES, LTD., A CORPORATION OF JAPAN (JP) | 2006-01-05 | — | — | US | disclosed |
| EP-1609775-A2 | 1-acetoxy-3-(substituted phenyl) propen compounds useful as an intermediate material | Ube Industries, Ltd. (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-1574509-A1 | PROCESS FOR THE PRODUCTION OF 1-ACETOXY-3-(SUBSTITUTED PHENYL)PROPENES | Ube Industries, Ltd. (JP) | 2005-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004213-A1 | 1-Acetoxy-3-(substituted phenyl)propene compounds | AKR1C3, P4HA1, AKR1C1 | SMN1; SMN2 4042/4885LMNA 1862/4885MAPT 4191/4885 |
| US-20060069273-A1 | Process for producing 1-acetoxy-3-(substituded phenyl) propenes | AKR1C4, PAH, AKR1C3 | SMN1; SMN2 2508/4885LMNA 2375/4885MAPT 3927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.