Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 6/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899407 | 0.80 | SMN1; SMN2 (0.61) | CCR3MEN1KMT2AMAPT | |
| SCHEMBL8014171 | 0.76 | CCR3 (0.66) | CCR3MEN1KMT2A | |
| SCHEMBL7608481 | 0.76 | CCR3 (0.66) | CCR3MEN1KMT2A | |
| SCHEMBL7898022 | 0.76 | SMN1; SMN2 (0.60) | MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL5580149 | 0.75 | CCR3 (0.49) | CCR3NR1H4MEN1KMT2AGAA | |
| SCHEMBL5580151 | 0.75 | CCR3 (0.49) | CCR3NR1H4MEN1KMT2AGAA | |
| SCHEMBL5580412 | 0.75 | CCR3 (0.48) | CCR3MEN1KMT2AGAAMAPT | |
| SCHEMBL5580414 | 0.75 | CCR3 (0.48) | CCR3MEN1KMT2AGAAMAPT | |
| SCHEMBL27689914 | 0.74 | SCN5A (0.54) | NR1H4MEN1KMT2A | |
| SCHEMBL29447178 | 0.74 | CCR3 (0.62) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313247-B1 | Cinchonan based chiral selectors for separation of stereoisomers | LINDNER WOLFGANG (AT) | 2001-11-06 | — | — | US | disclosed |