SCHEMBL7899407

SCHEMBL7899407

O=C(NCCc1ccc([N+](=O)[O-])cc1)c1cccc2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.61
RAB9A P51151 3/20 0.61
NPC1 O15118 2/20 0.61
TAAR1 Q96RJ0 1/20 0.61
ALDH1A1 P00352 3/20 0.54
HPGD P15428 2/20 0.54
MAPT P10636 4/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
CCR3 P51677 3/20 0.53
LMNA P02545 3/20 0.53
KDM4E B2RXH2 1/20 0.52
USP2 O75604 1/20 0.52
GSK3B P49841 1/20 0.52
KDM1A O60341 1/20 0.51
MAOA P21397 1/20 0.51
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13073501 0.84 RAB9A (0.63) RAB9ANPC1ALDH1A1HPGDMAPT
SCHEMBL27817831 0.83 NPC1 (0.65) SMN1; SMN2RAB9ANPC1TAAR1ALDH1A1
SCHEMBL11479124 0.81 PPARG (0.60) RAB9ANPC1HPGDMAPTLMNA
SCHEMBL7899403 0.80 CCR3 (0.53) MAPTMEN1KMT2ACCR3
SCHEMBL6962971 0.79 SMN1; SMN2 (0.89) SMN1; SMN2RAB9ANPC1TAAR1ALDH1A1
SCHEMBL6410116 0.78 SMN1; SMN2 (0.72) SMN1; SMN2RAB9ANPC1TAAR1ALDH1A1
SCHEMBL7608481 0.76 CCR3 (0.66) MEN1KMT2ACCR3
SCHEMBL8014171 0.76 CCR3 (0.66) MEN1KMT2ACCR3
SCHEMBL8192895 0.76 CCR3 (0.59) MAPTMEN1KMT2ACCR3
SCHEMBL11024162 0.76 RAB9A (1.00) SMN1; SMN2RAB9ANPC1TAAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313247-B1 Cinchonan based chiral selectors for separation of stereoisomers LINDNER WOLFGANG (AT) 2001-11-06 US disclosed