Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17020410 | 0.88 | CASP3 (0.62) | CASP3KMT2AEPHX2PIN1 | |
| SCHEMBL29068310 | 0.88 | CASP3 (0.64) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL29068308 | 0.88 | CASP3 (0.64) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL31697682 | 0.87 | CASP3 (0.60) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL13044090 | 0.87 | CASP3 (0.58) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL120703 | 0.87 | CASP3 (0.60) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL2591012 | 0.87 | CASP3 (0.58) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL10173305 | 0.87 | CASP3 (0.58) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL799720 | 0.87 | CASP3 (0.60) | CASP3KMT2AEPHX2PIN1MDM4 | |
| SCHEMBL178791 | 0.87 | CASP3 (0.60) | CASP3KMT2AEPHX2PIN1MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184345-B1 | STABLE UNDER SOLID PHASE SYNTHESIS CONDITIONS | PEPTOR LIMITED (IL) | 2001-02-06 | — | — | US | disclosed |
| EP-1037904-A2 | BRANCHED BUILDING UNITS FOR SYNTHESIZING CYCLIC PEPTIDES | PEPTOR LTD (IL) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999031121-A2 | BRANCHED BUILDING UNITS FOR SYNTHESIZING CYCLIC PEPTIDES | PEPTOR LTD. (IL) | 1999-06-24 | — | — | WO | disclosed |