Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15093308 | 0.87 | MEN1 (0.60) | CYP11B2CYP11B1NAMPTLRRK2LMNA | |
| SCHEMBL15093633 | 0.87 | NOTUM (0.60) | CYP11B2CYP11B1NAMPTLMNACXCR1 | |
| SCHEMBL15093148 | 0.85 | CYP11B2 (0.59) | CYP11B2CYP11B1NAMPTLMNACXCR1 | |
| SCHEMBL791892 | 0.80 | CYP11B1 (0.68) | CYP11B2CYP11B1NAMPTLMNACXCR1 | |
| SCHEMBL789625 | 0.80 | GRM5 (0.64) | CYP11B2CYP11B1NAMPTMEN1KMT2A | |
| SCHEMBL790643 | 0.79 | RAB9A (0.58) | CYP11B2CYP11B1NAMPTLMNACXCR1 | |
| SCHEMBL15093116 | 0.79 | CYP11B1 (0.60) | CYP11B2CYP11B1NAMPTLMNACXCR1 | |
| SCHEMBL790001 | 0.79 | SLC22A12 (0.41) | SLC22A12KMT2AMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL791160 | 0.78 | CYP11B1 (0.70) | CYP11B2CYP11B1LMNACXCR1CXCR2 | |
| SCHEMBL791672 | 0.77 | GRM5 (0.61) | CYP11B2CYP11B1CXCR1CXCR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2615917-A2 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS III | BASF SE (DE) | 2013-07-24 | — | — | EP | disclosed |
| US-20130180014-A1 | Pyridine Compounds for Controlling Invertebrate Pests III | BASF SE (DE) | 2013-07-11 | — | — | US | disclosed |
| WO-2012034959-A2 | PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS III | BASF SE (DE) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130180014-A1 | Pyridine Compounds for Controlling Invertebrate Pests III | CHRM1, CHRM2, GRIN2C | CYP11B2 308/4885CYP11B1 396/4885NAMPT 4575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.