Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 5/20 | 0.42 |
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7912756 | 0.90 | ESR1 (0.38) | PPARGPPARDPPARAESR1VDR | |
| SCHEMBL7899687 | 0.83 | NR1H2 (0.35) | PPARGPPARANR1H2NR1H3CYP3A4 | |
| SCHEMBL7908953 | 0.82 | VDR (0.47) | ESR1VDR | |
| SCHEMBL7899724 | 0.80 | ALDH1A1 (0.36) | ESR1VDRCYP3A4LMNASMN1; SMN2 | |
| SCHEMBL5495360 | 0.78 | PPARG (0.43) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL31296232 | 0.76 | ESR1 (0.45) | ESR1CYP3A4GABRA1GABRB2 | |
| SCHEMBL7906103 | 0.75 | ESR1 (0.38) | PPARGPPARDPPARAESR1VDR | |
| SCHEMBL7899686 | 0.74 | CYP3A4 (0.32) | CYP3A4USP2LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL346407 | 0.73 | SMN1; SMN2 (0.57) | CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL7907551 | 0.73 | CYP3A4 (0.38) | PPARGPPARDPPARAESR1VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187493-B1 | CHARGE GENERATING MATERIAL AND ELECTRON TRANSFER MATERIAL UNIFORMLY DISPERSED WITHIN COMPATIBLE POLYESTER BINDER; PHOTOSENSITIVITY, WEAR RESISTANCE, ADHESION TO ELECTROCONDUCTIVE SUBSTRATE | KYOCERA MITA CORPORATION (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0738934-A2 | Electrophotosensitive material | MITA INDUSTRIAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |