Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798867 | 0.88 | ALPL (0.48) | ALPLAAK1DGAT1PIK3CAPIK3CD | |
| SCHEMBL14860356 | 0.88 | ALPL (0.53) | ALPLAAK1DGAT1PIK3CAPIK3CD | |
| SCHEMBL789687 | 0.86 | ALPL (0.47) | ALPLAAK1DGAT1CYP17A1PIK3CA | |
| SCHEMBL791103 | 0.85 | ALPL (0.48) | ALPLAAK1DGAT1PIK3CAPIK3CD | |
| SCHEMBL109782 | 0.83 | ALPL (0.52) | ALPLPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL789432 | 0.81 | ALPL (0.52) | ALPLDGAT1CYP17A1PDGFRBKDR | |
| SCHEMBL15462779 | 0.79 | PIK3CA (0.51) | ALPLPIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL17022159 | 0.79 | SLC22A12 (0.60) | ALPLPIK3CASLC22A12 | |
| SCHEMBL789960 | 0.78 | ALPL (0.48) | ALPLAAK1PIK3CAPIK3CDPIK3CB | |
| SCHEMBL15559069 | 0.77 | ALPL (0.52) | ALPLPIK3CAPIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719385-A2 | 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINES AS ANTI-INFECTIOUS AGENTS | University of Vermont and State Agricultural College (US) | 2026-04-08 | — | — | EP | disclosed |
| CN-119585273-A | CD73 inhibitor compounds | 阿道尔克斯治疗有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2024249380-A2 | 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINES AS ANTI-INFECTIOUS AGENTS | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2024-12-05 | — | — | WO | disclosed |
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |
| EP-2958564-B1 | HETEROAROMATIC COMPOUNDS AS PI3 KINASE MODULATORS | CALITOR SCIENCES LLC (US) | 2018-05-09 | — | — | EP | disclosed |
| US-9573953-B2 | Heteroaromatic compounds as PI3 kinase modulators and methods of use | CALITOR SCIENCES, LLC (US) | 2017-02-21 | — | — | US | disclosed |
| WO-2016207081-A1 | IMINE DERIVATIVES AS HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-29 | — | — | WO | disclosed |
| EP-2958564-A1 | HETEROAROMATIC COMPOUNDS AS PI3 KINASE MODULATORS | Calitor Sciences, LLC (US) | 2015-12-30 | — | — | EP | disclosed |
| WO-2014130375-A1 | HETEROAROMATIC COMPOUNDS AS PI3 KINASE MODULATORS | CALITOR SCIENCES, LLC (US) | 2014-08-28 | — | — | WO | disclosed |
| US-20140234254-A1 | HETEROAROMATIC COMPOUNDS AS PI3 KINASE MODULATORS AND METHODS OF USE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2014-08-21 | — | — | US | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140234254-A1 | HETEROAROMATIC COMPOUNDS AS PI3 KINASE MODULATORS AND METHODS OF USE | PIK3R1, PIK3R3, AKT3 | ALPL 2207/4885AAK1 971/4885DGAT1 2356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.