Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | SELL | P14151 | 1/20 | 0.34 |
| ▸ | SELP | P16109 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899771 | 1.00 | TOP2A (0.39) | TOP2ATOP2BSLC6A2SLC5A2EPHX2 | |
| SCHEMBL7899770 | 0.90 | SLC6A2 (0.40) | SLC6A2SLC5A2PDPK1MTORSSTR5 | |
| SCHEMBL7154852 | 0.88 | SLC5A2 (0.45) | SLC6A2SLC5A2EPHX2SELLSELP | |
| SCHEMBL20643537 | 0.88 | SLC5A2 (0.45) | SLC6A2SLC5A2EPHX2SELLSELP | |
| SCHEMBL7133576 | 0.88 | SLC5A2 (0.45) | SLC6A2SLC5A2EPHX2SELLSELP | |
| SCHEMBL15671094 | 0.88 | SLC5A2 (0.45) | SLC6A2SLC5A2EPHX2SELLSELP | |
| SCHEMBL3642166 | 0.88 | SLC5A2 (0.45) | SLC6A2SLC5A2EPHX2SELLSELP | |
| SCHEMBL8359061 | 0.82 | PDPK1 (0.42) | SLC6A2PDPK1MTORSSTR5 | |
| SCHEMBL7899774 | 0.82 | PDPK1 (0.39) | SLC6A2PDPK1MTORSSTR5 | |
| SCHEMBL9503678 | 0.80 | SSTR5 (0.41) | SLC6A2PDPK1MTORSSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184365-B1 | 3,4-DI-O,N-PROTECTED-4-AMINO-2,4,6-TRIDEOXY-2-FLUORO-L-TALOPYR ANOSYL IODIDE OR BROMIDE; CHEMICAL INTERMEDIATES FOR PRODUCTION OF NOVEL DAUNOMYCINONE OR ADRIAMYCINONE DERIVATIVES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0848010-A1 | Novel anthracycline derivatives having 4-amino-2,4,6-trideoxy-2-fluoro-alpha-L-talopyranosyl group | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1998-06-17 | — | — | EP | disclosed |