Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | FGF1 | P05230 | 2/20 | 0.36 |
| ▸ | FGF2 | P09038 | 2/20 | 0.36 |
| ▸ | VEGFA | P15692 | 2/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670300 | 0.88 | SSTR1 (0.35) | PDPK1MTORSSTR5SSTR1SSTR2 | |
| SCHEMBL7899424 | 0.87 | SSTR5 (0.37) | PDPK1MTORSSTR5SSTR1SSTR2 | |
| SCHEMBL7892063 | 0.87 | SSTR1 (0.42) | PDPK1MTORSSTR5SSTR1SSTR2 | |
| SCHEMBL7899420 | 0.87 | SSTR5 (0.37) | PDPK1MTORSSTR5SSTR1SSTR2 | |
| SCHEMBL9503684 | 0.87 | SSTR1 (0.42) | PDPK1MTORSSTR5SSTR1SSTR2 | |
| SCHEMBL7899770 | 0.87 | SLC6A2 (0.40) | PDPK1MTORSSTR5SSTR1SSTR2 | |
| SCHEMBL8650408 | 0.86 | ALDH1A1 (0.42) | PDPK1MTORCYP2C19TSHR | |
| SCHEMBL7775231 | 0.86 | PDPK1 (0.45) | PDPK1MTORSSTR5SSTR1SSTR2 | |
| SCHEMBL24378456 | 0.84 | PDPK1 (0.47) | PDPK1MTORSSTR5SSTR1SSTR2 | |
| SCHEMBL7898143 | 0.83 | ALDH1A1 (0.41) | PDPK1MTORFGF1FGF2VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184365-B1 | 3,4-DI-O,N-PROTECTED-4-AMINO-2,4,6-TRIDEOXY-2-FLUORO-L-TALOPYR ANOSYL IODIDE OR BROMIDE; CHEMICAL INTERMEDIATES FOR PRODUCTION OF NOVEL DAUNOMYCINONE OR ADRIAMYCINONE DERIVATIVES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 2001-02-06 | — | — | US | claimed |
| US-6184365-B1 | 3,4-DI-O,N-PROTECTED-4-AMINO-2,4,6-TRIDEOXY-2-FLUORO-L-TALOPYR ANOSYL IODIDE OR BROMIDE; CHEMICAL INTERMEDIATES FOR PRODUCTION OF NOVEL DAUNOMYCINONE OR ADRIAMYCINONE DERIVATIVES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0848010-A1 | Novel anthracycline derivatives having 4-amino-2,4,6-trideoxy-2-fluoro-alpha-L-talopyranosyl group | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1998-06-17 | — | — | EP | disclosed |