SCHEMBL9503678

SCHEMBL9503678

CO[C@@H]1O[C@@H](C)[C@@H](OCc2ccccc2)[C@H](O)[C@H]1F

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SSTR5 P35346 2/20 0.41
SSTR1 P30872 1/20 0.41
SSTR2 P30874 1/20 0.41
SSTR4 P31391 1/20 0.41
SSTR3 P32745 1/20 0.41
LGALS8 O00214 1/20 0.41
BCHE P06276 4/20 0.39
SLC6A2 P23975 1/20 0.39
PDPK1 O15530 1/20 0.38
MTOR P42345 1/20 0.38
LGALS3 P17931 2/20 0.36
PTPN2 P17706 1/20 0.35
PTPN1 P18031 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C19 P33261 1/20 0.35
GJB2 P29033 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7892058 1.00 SSTR5 (0.41) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL19226930 0.89 SSTR5 (0.46) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL8328774 0.89 SSTR5 (0.46) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL2803784 0.89 LGALS8 (0.45) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL13129833 0.89 LGALS8 (0.45) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL19620385 0.89 SSTR5 (0.46) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL19620495 0.89 SSTR5 (0.46) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL7892063 0.88 SSTR1 (0.42) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL9503684 0.88 SSTR1 (0.42) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL8332110 0.83 SSTR5 (0.46) SSTR5SSTR1SSTR2SSTR4SSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0230322-B1 2,6-DIDEOXY-2-FLUORO-L-TALOPYRANOSE AND DERIVATES THEREOF AND THE PRODUCTION OF THESE COMPOUNDS ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1993-07-21 EP disclosed
EP-0230013-B1 NEW ANTHRACYCLINE DERIVATIVES, USES THEREOF AS ANTITUMOR AGENT AND PRODUCTION THEREOF ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1992-06-17 EP disclosed
US-5034517-A Process for producing 2,6-dideoxy-2-fluoro-L-talopyranose ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1991-07-23 US disclosed
EP-0230322-A2 2,6-Dideoxy-2-fluoro-L-talopyranose and derivates thereof and the production of these compounds ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1987-07-29 EP disclosed
EP-0230013-A1 New anthracycline derivatives, uses thereof as antitumor agent and production thereof ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1987-07-29 EP disclosed