Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 11/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.53 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.36 |
| ▸ | FEN1 | P39748 | 3/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791171 | 0.87 | PIK3CG (0.54) | PI4KAPIK3CGPTGES2PIK3CAMTOR | |
| SCHEMBL789985 | 0.81 | PIK3CG (0.81) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL790456 | 0.79 | PIK3CA (0.46) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL789984 | 0.75 | PI4KA (0.47) | PI4KAPIK3CGPTGES2PIK3CAMTOR | |
| SCHEMBL807190 | 0.75 | PIK3CG (0.79) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL791498 | 0.71 | PIK3CG (0.85) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL789570 | 0.69 | PIK3CG (1.00) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL789702 | 0.69 | PIK3CG (0.52) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL791281 | 0.69 | PIK3CG (0.80) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL790027 | 0.69 | PI4KA (0.46) | PI4KAPIK3CGPIK3CAALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |