Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 4/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.35 |
| ▸ | FEN1 | P39748 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790039 | 0.91 | PI4KA (0.44) | PI4KAPIK3CGTRPV1CA12CA1 | |
| SCHEMBL791132 | 0.87 | PI4KA (0.43) | PI4KAPIK3CGCA12CA1CA2 | |
| SCHEMBL790940 | 0.84 | PI4KA (0.41) | PI4KAPIK3CGCA12CA1CA2 | |
| SCHEMBL789502 | 0.80 | PIK3CG (0.59) | PI4KAPIK3CGPIK3CA | |
| SCHEMBL791171 | 0.78 | PIK3CG (0.54) | PI4KAPIK3CGKCNH2PIK3CA | |
| SCHEMBL791172 | 0.75 | PI4KA (0.68) | PI4KAPIK3CGPIK3CA | |
| SCHEMBL10277282 | 0.75 | PIK3CG (0.48) | PI4KAPIK3CGKCNH2PIK3CA | |
| SCHEMBL789599 | 0.75 | PI4KA (0.52) | PI4KAPIK3CGKCNH2PIK3CAFYN | |
| SCHEMBL796868 | 0.74 | PIK3CG (0.60) | PI4KAPIK3CGPIK3CA | |
| SCHEMBL790040 | 0.73 | PIK3CG (0.56) | PI4KAPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |