Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 13/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791169 | 0.88 | PIK3CG (0.47) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL790455 | 0.81 | PIK3CA (0.41) | PI4KAPIK3CGPIK3CAPIK3R1 | |
| SCHEMBL789986 | 0.75 | PI4KA (0.53) | PI4KAPIK3CGPIK3CAALOX5APFEN1 | |
| SCHEMBL789985 | 0.75 | PIK3CG (0.81) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL789700 | 0.70 | PIK3CG (0.45) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL807190 | 0.69 | PIK3CG (0.79) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL789481 | 0.69 | PI4KA (0.45) | PI4KAPIK3CG | |
| SCHEMBL789602 | 0.68 | PI4KA (0.41) | PI4KAPIK3CGMTOR | |
| SCHEMBL791498 | 0.66 | PIK3CG (0.85) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL806976 | 0.65 | PIK3CG (0.80) | PI4KAPIK3CGPIK3CAMTORPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |