Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984451 | 0.85 | ALDH1A1 (0.55) | ALDH1A1LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL2742576 | 0.85 | ALDH1A1 (0.62) | ALDH1A1LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL31090163 | 0.84 | SMN1; SMN2 (0.61) | ALDH1A1LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL10782766 | 0.83 | ALDH1A1 (0.60) | ALDH1A1LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL20718833 | 0.83 | ALDH1A1 (0.54) | ALDH1A1LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL2224074 | 0.82 | ATM (0.61) | ALDH1A1KMT2APLAAT3PLAAT5PLAAT2 | |
| SCHEMBL3949693 | 0.82 | ALDH1A1 (0.58) | ALDH1A1LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL498428 | 0.82 | SMN1; SMN2 (0.57) | ALDH1A1LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL2742574 | 0.81 | ALDH1A1 (0.61) | ALDH1A1LMNAGAAHTTSMN1; SMN2 | |
| SCHEMBL8867007 | 0.81 | SMN1; SMN2 (0.67) | ALDH1A1LMNAGAAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3441389-B1 | PYRAZOLE-OXAZOLIDINONE COMPOUND FOR ANTI-HEPATITIS B VIRUS | SHANGHAI ZHIMENG BIOPHARMA INC (CN) | 2021-09-08 | — | — | EP | disclosed |
| CN-109311865-B | Pyrazole-oxazolidinone compound for resisting hepatitis B virus | 上海挚盟医药科技有限公司 | 2021-08-31 | — | — | CN | disclosed |
| US-20190152963-A1 | PYRAZOLE-OXAZOLIDINONE COMPOUND FOR ANTI-HEPATITIS B VIRUS | SHANGHAI ZHIMENG BIOPHARMA, INC. (CN) | 2019-05-23 | — | — | US | disclosed |
| EP-3441389-A1 | PYRAZOLE-OXAZOLIDINONE COMPOUND FOR ANTI-HEPATITIS B VIRUS | Shanghai Zhimeng Biopharma Co., Ltd (CN) | 2019-02-13 | — | — | EP | disclosed |
| US-6232498-B1 | NOVEL CHEMICAL INTERMEDIATE | ASTRA ZENECA UK LIMITED (GB) | 2001-05-15 | — | — | US | disclosed |
| US-6194614-B1 | Process for the preparation of benzothiazolone compounds | ASTRAZENECA UK LIMITED (GB) | 2001-02-27 | — | — | US | disclosed |
| US-6147219-A | Process for the preparation of benzothiazolone compounds | ASTRAZENECA UK LIMITED (GB) | 2000-11-14 | — | — | US | disclosed |
| US-6124468-A | 7(2-ACETAMINOETHYL)-2-AMINO-4-METHOXYBENZOTHIAZINE INTERMEDIATE | ASTRAZENECA UK LIMITED (GB) | 2000-09-26 | — | — | US | disclosed |
| US-6118024-A | Process for the preparation of benzothiazolone compounds | ASTRAZENECA UK LIMITED (GB) | 2000-09-12 | — | — | US | disclosed |
| US-6114578-A | Process for the preparation of benzothiazolone compounds | ASTRAZENECA UK LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| US-6087508-A | Process for the preparation of benzothiazolone compounds | ASTRAZENECA UK LIMITED (GB) | 2000-07-11 | — | — | US | disclosed |
| EP-0970064-A1 | PROCESS FOR THE PREPARATION OF BENZOTHIAZOLONE COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998038180-A1 | PROCESS FOR THE PREPARATION OF BENZOTHIAZOLONE COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152963-A1 | PYRAZOLE-OXAZOLIDINONE COMPOUND FOR ANTI-HEPATITIS B VIRUS | HAVCR2, ZC3HAV1, ZC3HAV1L | ALDH1A1 795/4885LMNA 3781/4885GAA 3206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.