Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 17/20 | 1.00 |
| ▸ | MMP3 | P08254 | 15/20 | 1.00 |
| ▸ | MMP2 | P08253 | 17/20 | 0.78 |
| ▸ | MMP1 | P03956 | 6/20 | 0.74 |
| ▸ | MMP9 | P14780 | 2/20 | 0.74 |
| ▸ | MMP8 | P22894 | 1/20 | 0.74 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455389 | 0.88 | MMP13 (1.00) | MMP13MMP3MMP2MMP1MMP9 | |
| SCHEMBL7509269 | 0.86 | MMP13 (1.00) | MMP13MMP3MMP2MMP1MMP9 | |
| SCHEMBL7516814 | 0.85 | MMP13 (1.00) | MMP13MMP3MMP2MMP1MMP9 | |
| SCHEMBL7557397 | 0.83 | MMP13 (1.00) | MMP13MMP3MMP2MMP1MMP9 | |
| SCHEMBL7508941 | 0.83 | MMP13 (1.00) | MMP13MMP3MMP2MMP1MMP9 | |
| SCHEMBL7506978 | 0.82 | MMP2 (1.00) | MMP13MMP3MMP2MMP1MMP9 | |
| SCHEMBL31086921 | 0.79 | MMP13 (0.65) | MMP13MMP3MMP2MMP1MMP9 | |
| SCHEMBL31086930 | 0.79 | MMP13 (0.65) | MMP13MMP3MMP2MMP1MMP9 | |
| SCHEMBL7502956 | 0.79 | MMP13 (0.81) | MMP13MMP3MMP2MMP1MMP9 | |
| SCHEMBL7451531 | 0.79 | MMP13 (0.80) | MMP13MMP3MMP2MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | claimed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |