Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19321965 | 0.80 | HTR7 (0.57) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL8107984 | 0.79 | GRIA3 (0.56) | KMT2AGRIA3GRIA4 | |
| SCHEMBL12302043 | 0.78 | POLB (0.57) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL16708323 | 0.78 | POLB (0.57) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL12184226 | 0.78 | HTR7 (0.51) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL12184173 | 0.78 | HTR7 (0.51) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL12715936 | 0.78 | SMYD3 (0.52) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL8107156 | 0.77 | GRIA3 (0.58) | GRIA3GRIA4POLB | |
| SCHEMBL970132 | 0.77 | POLB (0.56) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL12156486 | 0.77 | POLB (0.59) | RAB9ANPC1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087980-A2 | BICYCLIC AMIDE DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DEPRESSION | CORTEX PHARMACEUTICALS, INC. (US) | 2010-08-05 | — | — | WO | disclosed |