SCHEMBL7900209

SCHEMBL7900209

c1ccc(-c2ccccc2-c2c3cc4ccccc4cc3c(-c3ccccc3-c3ccccc3)c3cc4ccccc4cc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.46
ESR2 Q92731 4/20 0.46
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 3/20 0.44
HPGD P15428 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 1/20 0.44
MPI P34949 1/20 0.44
TNF P01375 1/20 0.41
BACE1 P56817 1/20 0.41
NQO1 P15559 1/20 0.40
PTGS2 P35354 1/20 0.40
GPR84 Q9NQS5 3/20 0.40
HSD17B10 Q99714 3/20 0.39
MAPK1 P28482 2/20 0.39
BCL2L1 Q07817 1/20 0.39
CYP2A6 P11509 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29370611 0.96 ESR1 (0.47) ESR1ESR2ALDH1A1KDM4EHPGD
SCHEMBL7900283 0.96 ESR1 (0.47) ESR1ESR2ALDH1A1KDM4EHPGD
SCHEMBL7651425 0.87 ALDH1A1 (0.55) ESR1ESR2ALDH1A1KDM4EHPGD
SCHEMBL2725777 0.84 MEN1 (0.52) ESR1ESR2ALDH1A1KDM4EHPGD
SCHEMBL7900253 0.84 GPR84 (0.43) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL5497892 0.83 SOS1 (0.41) ESR1ESR2ALDH1A1KDM4EHPGD
SCHEMBL18858078 0.81 MAPK11 (0.43) ESR1ESR2ALDH1A1KDM4EHPGD
SCHEMBL16445344 0.81 ESR1 (0.42) ESR1ESR2ALDH1A1KDM4EHPGD
SCHEMBL26756017 0.81 HDAC4 (0.45) ESR1ESR2ALDH1A1KDM4EHPGD
SCHEMBL30394271 0.80 ESR1 (0.63) ESR1ESR2ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6203933-B1 ELECTROLUMINESCENT ELEMENT WITH LIGHT EMITTER LAYER AND HOLE INJECTING AND TRANSPORTATING COMPOUND TDK CORPORATION (JP) 2001-03-20 US disclosed