Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.40 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.39 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4580937 | 0.90 | NT5M (0.41) | TK1RNASE1NT5M | |
| SCHEMBL8931976 | 0.86 | TK1 (0.38) | TK1RNASE1NT5M | |
| SCHEMBL8931975 | 0.85 | TK1 (0.37) | TK1RNASE1NT5M | |
| SCHEMBL29703065 | 0.83 | TK1 (0.36) | TK1RNASE1NT5M | |
| SCHEMBL6832155 | 0.82 | TK2 (0.42) | TK1RNASE1 | |
| SCHEMBL9014399 | 0.82 | NT5M (0.43) | TK1RNASE1NT5M | |
| Doxribtimine SCHEMBL9386077 | 0.81 | TYMS (0.46) | TK1RNASE1 | |
| SCHEMBL2113756 | 0.80 | TK1 (0.42) | TK1RNASE1NT5M | |
| SCHEMBL8426287 | 0.79 | TK1 (0.45) | TK1RNASE1NT5M | |
| SCHEMBL9564565 | 0.78 | TK1 (0.52) | TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191266-B1 | MODIFIED TO COMPRISE SUBSTITUTIONS AT POSITIONS C1', C3', C4' OR C5' OF THE SUGAR MOIETY OF THE NUCLEOSIDE, INCLUDING AN OPTIONAL 3' PHOSPHOROAMIDITE GROUP; USE IN MAKING NUCLEASE RESISTANT OLIGONUCLEOTIDES FOR ANTISENSE THERAPY | ICN PHARMACEUTICALS, INC. | 2001-02-20 | — | — | US | disclosed |