Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.94 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.48 |
| ▸ | FEN1 | P39748 | 2/20 | 0.48 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520676 | 0.82 | KDM4E (0.67) | KDM4ELMNAPKMERCC1FEN1 | |
| SCHEMBL2216047 | 0.79 | KDM4E (0.61) | KDM4ELMNAPKMALDH1A1NPSR1 | |
| SCHEMBL7898975 | 0.78 | KDM4E (0.60) | KDM4ELMNAPKMERCC1FEN1 | |
| SCHEMBL7349965 | 0.73 | DAO (0.66) | KDM4EPKMERCC1FEN1ERCC4 | |
| SCHEMBL6382774 | 0.73 | DAO (0.65) | KDM4ELMNAPKMERCC1FEN1 | |
| SCHEMBL1520214 | 0.72 | ERCC1 (0.66) | KDM4ELMNAERCC1FEN1ERCC4 | |
| SCHEMBL7163743 | 0.71 | KDM4E (0.52) | KDM4ELMNAPKMERCC1FEN1 | |
| SCHEMBL10677691 | 0.71 | KDM4E (0.52) | KDM4ELMNAPKMERCC1FEN1 | |
| SCHEMBL7896638 | 0.71 | FEN1 (0.69) | KDM4EERCC1FEN1ERCC4DAO | |
| SCHEMBL7896123 | 0.70 | ALDH1A1 (0.54) | KDM4EERCC1FEN1ERCC4DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6183934-B1 | FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-02-06 | — | — | US | disclosed |