Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.55 |
| ▸ | FEN1 | P39748 | 2/20 | 0.55 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | RORA | P35398 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | RORB | Q92753 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2151350 | 0.81 | FEN1 (0.50) | KDM4EERCC1FEN1ERCC4PGR | |
| SCHEMBL7896638 | 0.80 | FEN1 (0.69) | KDM4EERCC1FEN1ERCC4CA12 | |
| SCHEMBL1408789 | 0.80 | GPR3 (0.52) | KDM4EERCC1FEN1ERCC4L3MBTL1 | |
| SCHEMBL7900407 | 0.78 | KDM4E (0.94) | KDM4EERCC1FEN1ERCC4CA12 | |
| Methane SCHEMBL151037 | 0.78 | BACE1 (0.50) | KDM4EERCC1FEN1ERCC4L3MBTL1 | |
| SCHEMBL7896123 | 0.76 | ALDH1A1 (0.54) | KDM4EERCC1FEN1ERCC4HSD17B10 | |
| Ethane SCHEMBL28032544 | 0.75 | GPR3 (0.55) | KDM4EERCC1FEN1ERCC4L3MBTL1 | |
| SCHEMBL2549113 | 0.75 | KDM4E (0.47) | KDM4EERCC1FEN1ERCC4CA12 | |
| Hydrochloric Acid SCHEMBL2553176 | 0.74 | KDM4E (0.46) | KDM4EERCC1FEN1ERCC4CA12 | |
| SCHEMBL346785 | 0.73 | GPR3 (0.65) | KDM4EERCC1FEN1ERCC4PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6183934-B1 | FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-02-06 | — | — | US | disclosed |