SCHEMBL7900508

SCHEMBL7900508

O=C1c2ccc(O)cc2C(=O)N1O

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 12/20 0.62
ESR2 Q92731 8/20 0.62
MAOA P21397 1/20 0.54
UGT1A1 P22309 1/20 0.54
MAOB P27338 1/20 0.54
ANPEP P15144 3/20 0.53
DPP4 P27487 3/20 0.53
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CRBN Q96SW2 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
APP P05067 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6651899 0.80 ESR1 (0.59) ESR1ESR2CA1CA2CA7
SCHEMBL3024023 0.80 APP (0.66) ESR1ESR2MAOAUGT1A1MAOB
SCHEMBL8649671 0.80 ESR1 (0.60) ESR1ESR2MAOAUGT1A1MAOB
SCHEMBL25060901 0.79 KDM4E (0.57) ESR1ESR2MEN1KMT2A
SCHEMBL9632877 0.78 ESR1 (0.96) ESR1ESR2ANPEPDPP4
SCHEMBL5530724 0.77 ESR1 (1.00) ESR1ESR2ANPEPDPP4MEN1
SCHEMBL42876 0.76 ALDH1A1 (0.55) ANPEPDPP4CRBNMEN1KMT2A
SCHEMBL3279383 0.76 CA9 (0.53) MAOAMAOBCA1CA2CA7
SCHEMBL31411903 0.76 CA9 (0.53) MAOAMAOBCA1CA2CA7
SCHEMBL2239437 0.76 S100A4 (0.52) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6183934-B1 FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE KABUSHIKI KAISHA TOSHIBA (JP) 2001-02-06 US disclosed