SCHEMBL7900524

SCHEMBL7900524

CCCCCc1cnc(-c2ccc(CCC)cc2)nc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.71
MAPT P10636 4/20 0.71
SMN1; SMN2 Q16637 4/20 0.71
ALDH1A1 P00352 3/20 0.71
KDM4E B2RXH2 3/20 0.71
HSD17B10 Q99714 3/20 0.71
MEN1 O00255 2/20 0.71
KMT2A Q03164 2/20 0.71
USP2 O75604 1/20 0.71
GAA P10253 1/20 0.71
HPGD P15428 1/20 0.71
RARB P10826 6/20 0.66
NPC1 O15118 3/20 0.51
NFKB1 P19838 2/20 0.51
NFKB2 Q00653 2/20 0.51
RELA Q04206 2/20 0.51
STAT3 P40763 1/20 0.51
ATM Q13315 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
CASP3 P42574 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7908259 1.00 RAB9A (0.71) RAB9AMAPTSMN1; SMN2ALDH1A1KDM4E
SCHEMBL7059794 0.97 MAPT (0.72) RAB9AMAPTSMN1; SMN2ALDH1A1KDM4E
SCHEMBL9637358 0.97 MAPT (0.72) RAB9AMAPTSMN1; SMN2ALDH1A1KDM4E
SCHEMBL10500474 0.97 RAB9A (0.68) RAB9AMAPTSMN1; SMN2ALDH1A1KDM4E
SCHEMBL10613205 0.95 RAB9A (0.66) RAB9AMAPTSMN1; SMN2ALDH1A1KDM4E
SCHEMBL10501582 0.95 MAPT (0.70) RAB9AMAPTSMN1; SMN2ALDH1A1KDM4E
SCHEMBL10501426 0.95 MAPT (0.70) RAB9AMAPTSMN1; SMN2ALDH1A1KDM4E
SCHEMBL9850283 0.95 MAPT (0.79) RAB9AMAPTSMN1; SMN2ALDH1A1KDM4E
SCHEMBL9840084 0.95 MAPT (0.79) RAB9AMAPTSMN1; SMN2ALDH1A1KDM4E
SCHEMBL9615976 0.95 MAPT (0.79) RAB9AMAPTSMN1; SMN2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5876626-A HIGH SPEED SWITCHING MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-03-02 US claimed
US-6210760-B1 SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2001-04-03 US disclosed
EP-0394417-B2 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 1999-08-04 EP disclosed
US-5876626-A HIGH SPEED SWITCHING MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-03-02 US disclosed
US-5387369-A With specified mixture of components; short switching times MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-02-07 US disclosed
EP-0394417-B1 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 1994-10-26 EP disclosed
EP-0366985-B1 Super twist liquid crystal display MERCK PATENT GMBH (DE) 1994-04-06 EP disclosed
EP-0338059-B1 IMPROVED LIQUID CRYSTAL MIXTURE CASIO COMPUTER COMPANY LIMITED (JP) 1993-04-21 EP disclosed
EP-0394417-A1 SUPERTWIST LIQUID CRYSTAL DISPLAY. MERCK PATENT GMBH (DE) 1990-10-31 EP disclosed
EP-0366985-A1 Super twist liquid crystal display MERCK PATENT GmbH (DE) 1990-05-09 EP disclosed
WO-1990004622-A1 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-05-03 WO disclosed
EP-0354940-A1 IMPROVED LIQUID CRYSTAL MIXTURE MERCK PATENT GmbH (DE) 1990-02-21 EP disclosed
EP-0338059-A1 IMPROVED LIQUID CRYSTAL MIXTURE CASIO COMPUTER COMPANY LIMITED (JP) 1989-10-25 EP disclosed
US-4853149-A STABILITY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-08-01 US disclosed
WO-1989006677-A1 IMPROVED LIQUID CRYSTAL MIXTURE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-07-27 WO disclosed
WO-1989003867-A1 IMPROVED LIQUID CRYSTAL MIXTURE CASIO COMPUTER COMPANY LIMITED (JP) 1989-05-05 WO disclosed