Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | RARB | P10826 | 6/20 | 0.67 |
| ▸ | RARA | P10276 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059794 | 1.00 | MAPT (0.72) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL7900524 | 0.97 | RAB9A (0.71) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL7908259 | 0.97 | RAB9A (0.71) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9229470 | 0.97 | MAPT (0.77) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL6665924 | 0.97 | MAPT (0.77) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9636394 | 0.97 | MAPT (0.77) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8596123 | 0.97 | MAPT (0.77) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9227943 | 0.97 | MAPT (0.77) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9637558 | 0.97 | MAPT (0.77) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9636397 | 0.97 | MAPT (0.77) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306917-B1 | A NEMATIC LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1992-06-17 | — | — | EP | disclosed |
| US-4917818-A | STEEP VOLTAGE TRANSMITTANCE USED IN WATCHES, ELECTRONIC CALCULATORS | CHISSO CORPORATION (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0306917-A2 | A nematic liquid crystal composition | CHISSO CORPORATION (JP) | 1989-03-15 | — | — | EP | disclosed |