SCHEMBL7900588

SCHEMBL7900588

CCCCCC1CCC(OC(=O)[C@]2(CCC)CC[C@H](C3CCCCC3)CC2)CC1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 5/20 0.40
CYP1A2 P05177 2/20 0.36
CCR2 P41597 1/20 0.33
PKM P14618 1/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
TP53 P04637 1/20 0.32
EPHX1 P07099 2/20 0.31
CPB2 Q96IY4 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7913856 0.95 NAAA (0.40) NAAACYP1A2CCR2PKMMEN1
SCHEMBL7910495 0.91 NAAA (0.34) NAAACYP2C19EPHX1CPB2
SCHEMBL10383950 0.89 NAAA (0.38) NAAACYP1A2HTTCYP2C19EPHX1
SCHEMBL7910467 0.89 NAAA (0.38) NAAACYP1A2HTTCYP2C19EPHX1
SCHEMBL8412372 0.82 NAAA (0.39) NAAACYP1A2CCR2PKMMEN1
SCHEMBL11097035 0.81 NAAA (0.43) NAAACYP1A2HTTCYP2C19EPHX1
SCHEMBL8413840 0.80 NAAA (0.39) NAAACYP1A2CCR2PKMMEN1
SCHEMBL9758508 0.80 CYP4F2 (0.39) NAAACYP1A2CCR2PKMMEN1
SCHEMBL9759035 0.79 CYP4F2 (0.41) NAAACYP1A2CCR2PKMMEN1
SCHEMBL9758111 0.79 CYP4F2 (0.41) NAAACYP1A2CCR2PKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6210760-B1 SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2001-04-03 US disclosed
US-5876626-A HIGH SPEED SWITCHING MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-03-02 US disclosed
US-5387369-A With specified mixture of components; short switching times MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-02-07 US disclosed
US-5030383-A With low temperature dependence of threshold voltage MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-07-09 US disclosed
US-4985583-A Liquid Crystals MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-01-15 US disclosed
US-4877547-A Liquid crystal display element MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-10-31 US disclosed
US-4871472-A Esters in ferroelectric mixtures MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-10-03 US disclosed
US-4737311-A Liquid crystal phase MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-04-12 US disclosed
US-4735966-A ANTICOAGULANTS, VASODILATORS, HYPOTENSIVE AND ANTICHOLESTEROL AGENTS SYNTEX (U.S.A.) INC. (US) 1988-04-05 US disclosed
US-4726911-A Heterocyclic compounds MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-02-23 US disclosed
US-4719032-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-01-12 US disclosed
US-4622163-A Anisotropic compounds and liquid crystal mixtures MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-11-11 US disclosed