SCHEMBL7910495

SCHEMBL7910495

CCCC1CCC(OC(=O)[C@]2(CCC)CC[C@H](C3CCCCC3)CC2)CC1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.34
EPHX1 P07099 1/20 0.33
CYP2C19 P33261 1/20 0.32
CPB2 Q96IY4 1/20 0.31
TLR4 O00206 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10383950 0.93 NAAA (0.38) NAAAEPHX1CYP2C19CPB2
SCHEMBL7910467 0.93 NAAA (0.38) NAAAEPHX1CYP2C19CPB2
SCHEMBL7900588 0.91 NAAA (0.40) NAAAEPHX1CYP2C19CPB2
SCHEMBL7913856 0.86 NAAA (0.40) NAAAEPHX1CYP2C19CPB2
SCHEMBL8413983 0.81 NAAA (0.33) NAAAEPHX1CYP2C19TLR4
SCHEMBL10609931 0.79 NAAA (0.34) NAAA
SCHEMBL19837775 0.79 CYP2C19 (0.46) NAAAEPHX1CYP2C19
SCHEMBL8411044 0.77 NAAA (0.37) NAAAEPHX1CYP2C19
SCHEMBL11097035 0.76 NAAA (0.43) NAAAEPHX1CYP2C19
SCHEMBL9502480 0.75 CYP2C19 (0.33) NAAAEPHX1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6210760-B1 SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2001-04-03 US disclosed
US-5876626-A HIGH SPEED SWITCHING MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-03-02 US disclosed
US-5387369-A With specified mixture of components; short switching times MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-02-07 US disclosed
US-5204019-A Liquid crystals MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-04-20 US disclosed
US-5108652-A Liquid crystal dielectrics Merck patent Gesellschaft mit beschrankter Haftung Darmstadt (DE) 1992-04-28 US disclosed
US-5030383-A With low temperature dependence of threshold voltage MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-07-09 US disclosed
US-4986931-A Cyclohexane derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-01-22 US disclosed
US-4985583-A Liquid Crystals MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-01-15 US disclosed
US-4877547-A Liquid crystal display element MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-10-31 US disclosed
US-4871472-A Esters in ferroelectric mixtures MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-10-03 US disclosed
US-4737311-A Liquid crystal phase MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-04-12 US disclosed
US-4726911-A Heterocyclic compounds MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-02-23 US disclosed
US-4719032-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-01-12 US disclosed
US-4622163-A Anisotropic compounds and liquid crystal mixtures MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-11-11 US disclosed
US-4600528-A Decalin-carbonitriles MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-07-15 US disclosed
US-4510069-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1985-04-09 US disclosed