Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | RORC | P51449 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913990 | 0.86 | RORC (0.52) | NPSR1KDM4EKMT2AMEN1POLB | |
| SCHEMBL9551008 | 0.83 | KDM4E (0.50) | NPSR1KDM4EKMT2AMEN1POLB | |
| SCHEMBL4420346 | 0.81 | SMN1; SMN2 (0.64) | NPSR1KDM4EKMT2AMEN1POLB | |
| SCHEMBL7900520 | 0.80 | MAPT (0.51) | KDM4EKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL8942551 | 0.79 | ALDH1A1 (0.55) | NPSR1KDM4EKMT2AMEN1GAA | |
| SCHEMBL25434777 | 0.78 | SMN1; SMN2 (0.47) | NPSR1KDM4EKMT2AMEN1POLB | |
| SCHEMBL29074676 | 0.78 | SMN1; SMN2 (0.47) | NPSR1KDM4EKMT2AMEN1POLB | |
| SCHEMBL6809200 | 0.77 | CYP1A2 (0.53) | NPSR1KDM4EKMT2AMEN1POLB | |
| SCHEMBL6639628 | 0.77 | CYP1A2 (0.53) | NPSR1KDM4EKMT2AMEN1POLB | |
| SCHEMBL6587015 | 0.75 | KDM4E (0.54) | NPSR1KDM4EKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211397-B1 | CHLORINATION OF PHOSPHORANES | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-03 | — | — | US | disclosed |
| US-5569774-A | Process for the preparation of chlorine-substituted olefins | BASF AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | disclosed |