Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900730 | 1.00 | KCNH2 (0.41) | KCNH2LIPGALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7894775 | 1.00 | KCNH2 (0.41) | KCNH2LIPGALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7894780 | 1.00 | KCNH2 (0.41) | KCNH2LIPGALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7904030 | 1.00 | KCNH2 (0.41) | KCNH2LIPGALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7900732 | 1.00 | KCNH2 (0.41) | KCNH2LIPGALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7902229 | 0.91 | KCNH2 (0.34) | KCNH2LIPGCYP1A2CYP2C19SLC9A1 | |
| SCHEMBL7902228 | 0.91 | KCNH2 (0.34) | KCNH2LIPGCYP1A2CYP2C19SLC9A1 | |
| SCHEMBL7902844 | 0.91 | KCNH2 (0.34) | KCNH2LIPGCYP1A2CYP2C19SLC9A1 | |
| SCHEMBL15659429 | 0.88 | ALDH1A1 (0.38) | KCNH2LIPGALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7609751 | 0.87 | SMN1; SMN2 (0.36) | KCNH2LIPGSLC9A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194593-B1 | USEFUL AS LIGAND FOR AN ASYMMETRIC CATALYST FOR USE IN ASYMMETRICAL HYDROGENATION | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |