SCHEMBL7609751

SCHEMBL7609751

CCCCCCP(C)c1ccccc1F

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
KCNH2 Q12809 3/20 0.35
GRM2 Q14416 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
ICMT O60725 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
FAAH O00519 6/20 0.32
TLR8 Q9NR97 1/20 0.32
NPC1 O15118 1/20 0.32
MITF O75030 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SLC9A1 P19634 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7900732 0.87 KCNH2 (0.41) SMN1; SMN2MEN1KMT2AKCNH2LIPG
SCHEMBL7900733 0.87 KCNH2 (0.41) SMN1; SMN2MEN1KMT2AKCNH2LIPG
SCHEMBL7904030 0.87 KCNH2 (0.41) SMN1; SMN2MEN1KMT2AKCNH2LIPG
SCHEMBL7900730 0.87 KCNH2 (0.41) SMN1; SMN2MEN1KMT2AKCNH2LIPG
SCHEMBL7894775 0.87 KCNH2 (0.41) SMN1; SMN2MEN1KMT2AKCNH2LIPG
SCHEMBL7894780 0.87 KCNH2 (0.41) SMN1; SMN2MEN1KMT2AKCNH2LIPG
SCHEMBL5716176 0.86 ICMT (0.37) SMN1; SMN2MEN1KMT2AKCNH2HDAC3
SCHEMBL7612849 0.84 SMN1; SMN2 (0.36) SMN1; SMN2MEN1KMT2AKCNH2GRM2
SCHEMBL15659429 0.80 ALDH1A1 (0.38) KCNH2LIPGTLR8SLC9A1
SCHEMBL7902228 0.78 KCNH2 (0.34) SMN1; SMN2MEN1KMT2AKCNH2LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed