SCHEMBL7900841

SCHEMBL7900841

C[C@@H](NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NC(Cc1ccccc1)C(=O)NCC(N)=O

nearest known ligand 0.74

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 15/20 0.74
OPRM1 P35372 8/20 0.74
OPRK1 P41145 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30938810 1.00 OPRD1 (0.74) OPRD1OPRM1OPRK1
SCHEMBL29394698 0.93 OPRD1 (0.76) OPRD1OPRM1OPRK1
SCHEMBL29973200 0.93 OPRD1 (0.76) OPRD1OPRM1OPRK1
SCHEMBL31140206 0.89 OPRD1 (0.80) OPRD1OPRM1OPRK1
Casokefamide SCHEMBL1373200 0.88 OPRD1 (0.69) OPRD1OPRM1OPRK1
SCHEMBL29440670 0.88 OPRD1 (0.69) OPRD1OPRM1OPRK1
Deltorphin C SCHEMBL27459098 0.87 OPRD1 (0.83) OPRD1OPRM1OPRK1
SCHEMBL30661444 0.87 OPRD1 (0.70) OPRD1OPRM1OPRK1
SCHEMBL30786035 0.87 OPRD1 (0.69) OPRD1OPRM1OPRK1
Deltorphin Ii SCHEMBL31206794 0.86 OPRD1 (0.73) OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184208-B1 PENTAPEPTIDE OF FORMULA X-TYROSINE-Y-PHENYLALANINE-Z-A WHERE A IS OH OR NH2, AND X, Y, AND Z ARE CHOSEN FROM SPECIFIED AMINO ACIDS; ADMINISTERING TO STIMULATE PHYSIOLOGICAL PROCESSES SUCH AS WEIGHT GAIN, HAIR GROWTH, AND WOUND HEALING IMMUNOTECH DEVELOPMENTS INC. (CA) 2001-02-06 US disclosed